Browsing by Author "Sant'Ana, Helena Maria Pinheiro"
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Item Conteúdo de riboflavina em leite e produtos lácteos e comparação com o valor anunciado no rótulo.(2008) Abranches, Monise Viana; Lucia, Ceres Mattos Della; Rocha, Fernanda Izabel Garcia da; Moraes, Vanessa Barbosa de; Gonçalves, Lisângela Fernandes; Neves, Érica Granato Faria; Sant'Ana, Helena Maria PinheiroO leite e seus derivados são alimentos de alto valor nutricional, muito presentes na dieta do brasileiro e ricos em ribofl avina, cuja defi ciência é endêmica em várias regiões do mundo. Esse estudo investigou o conteúdo de ribofl avina em leites e derivados e avaliou se os valores encontrados são condizentes com os declarados no rótulo. Foram avaliadas 3 marcas de leite integral, 2 de leite desnatado, 2 de queijo tipo petit suisse e 3 de iogurte. As análises foram conduzidas por Cromatografi a Liquida de Alta Efi ciência (CLAE). Não foi observada diferença quanto ao conteúdo de ribofl avina entre os leites desnatados, mesmo quando apresentado no rótulo o termo “enriquecido com vitaminas”. O mesmo não foi observado em leites integrais, sendo encontradas diferenças signifi cativas quanto ao conteúdo vitamínico entre as marcas analisadas. Em iogurtes, esta diferença não foi signifi cativa. Uma das marcas de queijo tipo petit suisse apresentou teor de ribofl avina duas vezes superior à outra. Notou-se superestimação dos valores de ribofl avina descritos nos rótulos dos produtos que continham esta informação quando comparados àqueles encontrados no presente trabalho. Verifi ca-se a necessidade de fi scalização quanto ao enriquecimento de produtos lácteos e de intensifi car as pesquisas nessa área, devido à escassez de dados na literatura.Item Dietary açai attenuates hepatic steatosis via adiponectin-mediated effects on lipid metabolism in high-fat diet mice.(2015) Guerra, Joyce Ferreira da Costa; Maciel, Poliane Silva; Abreu, Isabel Cristina Mallosto Emerich de; Pereira, Renata Rebeca; Silva, Maísa; Cardoso, Leandro de Morais; Sant'Ana, Helena Maria Pinheiro; Lima, Wanderson Geraldo de; Silva, Marcelo Eustáquio; Pedrosa, Maria LúciaPolyphenols, especially anthocyanins, have been considered promising for the prevention of nonalcoholic fatty liver disease (NAFLD). This study investigated whether açai (Euterpe oleracea Mart.), a source of anthocyanins and recognized as one of the new “superfruits”, could alleviate high-fat diet (HFD)-induced NAFLD in mice. In HFD mice, aqueous açai extract (AAE) administration (3 g/kg) for six weeks improved insulin resistance index and increased adiponectin mRNA expression in adipose tissue and serum levels. Furthermore, AAE decreased the total liver triacylglycerol content and attenuated HFD-induced hepatic steatosis. This reduced hepatic lipid content was associated with AAE-mediated up-regulation of genes involved in adiponectin signaling, including adiponectin receptor 2, PPAR-α, and its target gene, carnitine palmitoyltransferase. Thus, dietary açai can protect liver from steatosis through its enhancement of adiponectin levels, improvement of insulin sensitivity, and increase in PPAR-α-mediated fatty acid oxidation.Item Dietary folate intake is negatively associated with excess body weight in brazilian graduates and postgraduates (CUME project).(2019) Pereira, Gabriela Amorim; Bressan, Josefina; Oliveira, Fernando Luiz Pereira de; Sant'Ana, Helena Maria Pinheiro; Pimenta, Adriano Marçal; Lopes, Liliane Teixeira; Hermsdorff, Helen Hermana MirandaFolate, vitamin B6, and vitamin B12 intake can be important regulators for obesity development. Thus, we investigated the possible association between the intake of these vitamins and the excess body weight or obesity prevalence in the participants of the Cohort of Universities in Minas Gerais (CUME project). This study analyzed cross-sectional data of 2695 graduates and postgraduates from universities in the state of Minas Gerais (801 men, 1894 women, ages 36.2 ± 9.4). The first step consisted of collecting data online, and the second step consisted of blood collecting in the subsample living in the city of Viçosa and its region (Minas Gerais). Excess body weight and obesity prevalence were 38.1% and 10.1%, respectively. Inadequate intake of folate, B6, and B12 were 12, 6.3, and 11.1%, respectively. Beans/lentils and French bread presented the highest contribution to folate intake (23.45% and 10.01%, respectively). Those individuals in the third tertile for folate intake (≥511.12 µg/d) had a lower excess body weight [prevalence ratio (PR): 0.79, confidence interval (CI): 0.71–0.8] and obesity prevalence (PR: 0.60, CI: 0.45–0.78). These associations were maintained when the sample was categorized by sex. In addition, serum folate was positively associated with dietary folate (p for trend = 0.032) and negatively associated with serum homocysteine (p for trend = 0.003) in the subsample. Dietary folate intake was negatively associated with excess body weight and obesity in CUME participants, indicating the relevance of this vitamin dietary assessment.