Browsing by Author "Silva, Adriana Carneiro"

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    Antinociceptive and anti-inflammatory activities of ethanolic extracts of Lychnophora species.
    (2008) Guzzo, Luciana Souza; Guimarães, Dênia Antunes Saúde; Silva, Adriana Carneiro; Lombardi, Júlio Antônio; Guimarães, Homero Nogueira; Guimarães, Andrea Grabe
    Extracts from Lychnophora species are traditionally used in Brazil as anti-inflammatory, and to treat bruise, pain and rheumatism. The ethanolic extract of aerial parts of five species of Lychnophoras and one specie of Lychnophoriopsis were examined for the antinociceptive (hot-plate and writhing tests) and anti-inflammatory (carrageenan-induced paw oedema test) activity in mice, by oral and topical routes, respectively. In the hot-plate test, the Lychnophora pinaster (0.75 g/kg) and Lychnophora ericoides (1.50 g/kg) extracts significantly increased the time for licking of the paws. The species Lychnophora passerina, Lychnophoriopsis candelabrum and Lychnophora pinaster, using the dose of 0.75 g/kg, and Lychnophora ericoides and Lychnophora trichocarpha in both doses evaluated (0.75 and 1.50 g/kg) significantly reduced the number of writhes induced by acetic acid. The administration of Lychnophora pinaster and Lychnophora trichocarpha ointments, in both concentrations evaluated (5 and 10%, w/w), and Lychnophora passerina and Lychnophoriopsis candelabrum, in the concentration of 10%, significantly reduced the paw oedema measured 3 h after carrageenan administration, suggesting, for the first time, an anti-inflammatory activity upon topical administration of these species. The present work comparatively demonstrated the antinociceptive and anti-inflammatory activities of some Brazilian Lychnophoras.
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    Medicamentos anti-hipertensivos utilizados na área rural de Ouro Preto, MG.
    (2007) Silva, Adriana Carneiro; Pereira, Roberta Verciano; Figueiredo, Bárbara de Castro Pimentel; Couto, Wagner Faria; Gramigna, Luísa Leite; Sana, Dandara Emery Morais; Gomes, Rodrigo Saar; Andrade, Graziela de Fátima; Brant, João Francisco de Avelar Caldeira; Breguez, Gustavo Silveira; Silva, Mariana Augusta Resende; Barbeitos, Priscila Oliveira; Junior, Luiz Carlos Pereira; Reis, Levi Eduardo Soares; Jayme, Marisa Ferrareto; Camargo, Rúbia Santos; Franco, Marcelo Nóbile; Amaral, Murilo Sena; Carneiro, Cláudia Martins; Guimarães, Andrea Grabe