Effect of physical exercise on lipid metabolism in rats submitted to hypercholesterolemic diet.
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Date
2006
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Abstract
The so-called dislipedemias have been appointed as a factor causing chronic degenerative
diseases as
Coronarian Arterial Disease (CAD) and other aterosclerotic diseases. Hypercholesterolemia is a
kind of dislipidemia characterized by a high concentration of LDL serum cholesterol, causing
aterogenesis and increasing the risk of CAD. Physicalactivity has been demonstratedto act
beneficially on the factors leading to chronic degenerative diseases and having its effect
potentialized when combined with a balanced diet. In the present work 48 female Fisher adult rats
were distributed into four groups: Execice (swimming 30 min/day, 5 days/week) with
Hypercholesterolemic Diet, Exercice with Control Diet, Sedentary with Hypercholesterolemic Diet and
Sedentary with Control Diet. After 9 weeks the animals were sacrificed. The obtained results show
that exercice was efficient in reducing total cholesterol, influenced in the wheight of soleo
muscle and there was indication of effect on the oxidative stress as shown by increase in the concentration
reduction of paraoxonase activity.The results indicate that low intensity training is capable of
alter profile and suggest that new studies be made with different volumes and intensities of
training.
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Keywords
Dislipidemia
Citation
GONÇALVES, A. C. et al. Effect of physical exercise on lipid metabolism in rats submitted to hypercholesterolemic diet. The FIEP Bulletin, Brasil, v. 76, n.special ed, p. 186-189, 2006. Disponível em: <http://www.fiepbulletin.net/index.php/fiepbulletin/article/view/5087>. Acesso em: 23 fev. 2017.