Temporal analysis of oxidative effects on the pulmonary inflammatory response in mice exposed to cigarette smoke.

Simple item page
dc.contributor.authorCampos, Keila Karine Duarte
dc.contributor.authorManso, Rafaela Gontijo
dc.contributor.authorGonçalves, Evandro Guedes
dc.contributor.authorSilva, Marcelo Eustáquio
dc.contributor.authorLima, Wanderson Geraldo de
dc.contributor.authorMenezes, Cristiane Alves da Silva
dc.contributor.authorBezerra, Frank Silva
dc.date.accessioned2015-01-22T15:12:17Z
dc.date.available2015-01-22T15:12:17Z
dc.date.issued2013
dc.description.abstractThe most common factor related to the chronic obstructive pulmonary disease (COPD) development is the chronic smoking habit. Our study describes the temporal kinesis of pulmonary cellular influx through BALF analyses of mice acutely exposed to cigarette smoke (CS), the oxidative damage and antioxidative enzyme activities. Thirty-six mice (C57BL/6, 8 weeks old, male) were divided in 6 groups: the control group (CG), exposed to ambient air, and the other 30 mice were exposed to CS. Mice exposed to CS presented, especially after the third day of exposure, different cellular subpopulations in BALF. The oxidative damage was significantly higher in CS exposed groups compared to CG. Our data showed that the evaluated inflammatory cells, observed after three days of CS exposure, indicate that this time point could be relevant to studies focusing on these cellular subpopulation activities and confirm the oxidative stress even in a short term CS exposure.pt_BR
dc.identifier.citationCAMPOS, K. K. D. et al. Temporal analysis of oxidative effects on the pulmonary inflammatory response in mice exposed to cigarette smoke. Cellular Immunology, v. 284, p. 29-36, 2013. Disponível em: <http://www.sciencedirect.com/science/article/pii/S0008874913001172>. Acesso em: 08 nov. 2014.pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.cellimm.2013.07.002
dc.identifier.issn0008-8749
dc.identifier.urihttp://www.repositorio.ufop.br/handle/123456789/4350
dc.language.isoen_USpt_BR
dc.rights.licenseO periódico Cellular Immunology concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3520371206808.pt_BR
dc.subjectCigarette smokept_BR
dc.subjectFlow cytometrypt_BR
dc.subjectLung inflammationpt_BR
dc.subjectOxidative stresspt_BR
dc.subjectMicept_BR
dc.titleTemporal analysis of oxidative effects on the pulmonary inflammatory response in mice exposed to cigarette smoke.pt_BR
dc.typeArtigo publicado em periodicopt_BR
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
ARTIGO_TemporalAnalysisOxidative.pdf
Size:
1.03 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
2.57 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
DECBI - Artigos publicados em periódicos