Borderline personality features possibly related to cingulate and orbitofrontal cortices dysfunction due to schizencephaly.
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Date
2008
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Abstract
Prefrontal cortex dysfunction has been associated with a series of behavioral symptoms, such as impulsivity and affective instability, which are the defining features of several personality disorders, notably, borderline personality disorder. We report on a 27-year-old patient with schizencephaly in the right frontal lobe (cingulate cortex lesion and secondary orbitofrontal cortex dysfunction) presenting with prominent borderline features and compromise of executive functions, decision-making and attention. We hypothesize that the personality disorder of our patient could be related to cingulate cortex lesion and secondary orbitofrontal cortex dysfunction associated with schizencephaly.
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Keywords
Schizencephaly, Impulsivity, Borderline personality, Orbitofrontal cortex, Cingulate cortex
Citation
ROCHA, F. F. et al. Borderline personality features possibly related to cingulate and orbitofrontal cortices dysfunction due to schizencephaly. Clinical Neurology and Neurosurgery (Dutch-Flemish ed.), v. 110, p. 396-399, 2008. Disponível em: <http://www.sciencedirect.com/science/article/pii/S0303846707003629#>. Acesso em: 03 set. 2014.