Paracoccidioidomycosis case series with and without central nervous system involvement.

Simple item page
dc.contributor.authorPedroso, Vinicius Sousa Pietra
dc.contributor.authorLyon, Ana Cláudia
dc.contributor.authorAraújo, Stanley de Almeida
dc.contributor.authorVeloso, Juliana Márcia Ribeiro
dc.contributor.authorPedroso, Enio Roberto Pietra
dc.contributor.authorTeixeira, Antônio Lúcio
dc.date.accessioned2014-11-12T18:41:45Z
dc.date.available2014-11-12T18:41:45Z
dc.date.issued2012
dc.description.abstractIntroduction: Paracoccidioidomycosis (PCM) is the most important systemic mycosis in South America. Central nervous system involvement is potentially fatal and can occur in 12.5% of cases. This paper aims to contribute to the literature describing eight cases of neuroparacoccidioidomycosis (NPMC) and compare their characteristics with patients without neurological involvement, to identify unique characteristics of NPCM. Methods: A cohort of 213 PCM cases was evaluated at the Infectious Diseases Clinic of the University Hospital, Federal University of Minas Gerais, Brazil, from October 1976 to August 2008. Epidemiological, clinical, laboratory, therapeutic and follow-up data were registered. Results: Eight patients presented NPCM. The observed NPCM prevalence was 3.8%. One patient presented the subacute form of PCM and the other seven presented the chronic form of the disease. The parenchymatous form of NPCM occurred in all patients. 60% of the patients who proceeded from the north/ northeast region of Minas Gerais State developed NPCM. The neurological involvement of a mother and her son was observed. NPCM patients exhibited demographical and clinical profiles similar to what is described in the literature. When NPCM cases were compared to PCM patients, there were differences in relation to origin and positive PCM family history. Conclusions: The results corroborate the clinical view that the neurological findings are extremely important in the evaluation of PCM patients. Despite the limitations of this study, the differences in relation to patient’s origins and family history point to the need of further studies to determine the susceptibility factors involved in the neurological compromise.pt_BR
dc.identifier.citationPEDROSO, V. S. P. et al. Paracoccidioidomycosis case series with and without central nervous system involvement. Revista da Sociedade Brasileira de Medicina Tropical, v. 45, p. 586-590, 2012. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822012000500009&lng=en&nrm=iso&tlng=en>. Acesso em: 08 set. 2014.pt_BR
dc.identifier.doihttp://dx.doi.org/10.1590/S0037-86822012000500009
dc.identifier.issn0037-8682
dc.identifier.urihttp://www.repositorio.ufop.br/handle/123456789/3818
dc.language.isoen_USpt_BR
dc.rights.licenseA Revista da Sociedade Brasileira de Medicina Tropical permite o depósito das versões pré-print e pós-print de um artigo. Permite remixagem, adaptação e nova criação a partir da obra para fins não comerciais desde que seja atribuído o crédito ao autor (CC BY-NC). Fonte: Diadorim <http://diadorim.ibict.br/handle/1/127>. Acesso em: 10 fev. 2020.pt_BR
dc.subjectParacoccidioidomycosispt_BR
dc.subjectNeuroparacoccidioidomycosispt_BR
dc.subjectEpidemiologypt_BR
dc.subjectCase seriespt_BR
dc.titleParacoccidioidomycosis case series with and without central nervous system involvement.pt_BR
dc.typeArtigo publicado em periodicopt_BR
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
ARTIGO_ParacoccidioidomycosisCase Series.pdf
Size:
737.07 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
DECPA - Artigos publicados em periódicos