Pulmonary functional assessment : longitudinal study after treatment of pulmonary tuberculosis.
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Date
2021
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Abstract
Even when treated adequately, pulmonary tuberculosis can lead to pulmonary sequelae.
Patients treated for PTB between 2012 and 2016 answered a standardized questionnaire and
underwent chest radiography and spirometry, measurement of absolute pulmonary volume,
Diffusing Capacity for Carbon Monoxide (DLCO) and the 6-min walk test (6MWT) on two
occasions: within the first year after the end of treatment (follow-up 1), and one and two
years after follow-up 1 (follow-up 2). A total of 55 patients they underwent spirometry, 23
(41.82%) had obstructive ventilatory disorder (OVD) and eight (14.5%) had moderate OVD.
In total, 29 patients underwent pulmonary function tests (PFTs) and 24 patients underwent
the 6MWT on two occasions. The functional changes after PTB treatment appear not to
have varied between one and two years of follow-up. There was a correlation between low
FEV1
and low DLCO (p<0.001); low DLCO and low 6MWT (p<0.001) and radiographic
abnormalities and low FEV1
(p=0.033). The most frequently observed change in spirometry
was found in patients with OVD.
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Keywords
Spirometry, 6-minute walk test, Lung capacity, Tuberculosis sequelae
Citation
NISHI, M. P. et al. Pulmonary functional assessment: longitudinal study after treatment of pulmonary tuberculosis. Revista do Instituto de Medicina Tropical de São Paulo, v. 63, artigo e65, 2021. Disponível em: <https://www.scielo.br/j/rimtsp/a/QsgnS7RsFJSyhd5wvscGMpK/?lang=en>. Acesso em: 11 out. 2022.