Facile synthesis of symmetrical 3,3-diarylacrylates by a Heck-Matsuda reaction : an expedient route to biologically active indanones.

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dc.contributor.authorTaylor, Jason Guy
dc.contributor.authorRibeiro, Rodrigo da Silva
dc.contributor.authorCorreia, Carlos Roque Duarte
dc.date.accessioned2015-04-09T11:00:01Z
dc.date.available2015-04-09T11:00:01Z
dc.date.issued2011
dc.description.abstractA simple and straightforward synthesis of symmetrical 3,3-diarylacrylates based on a Heck-Matsuda reaction of arenediazonium salts bearing electron-donating groups with methylacrylates is described. The reaction employs Pd(OAc)2 as catalyst and goes to completion within 1 h affording the corresponding unsaturated diaryl esters in good to high yields. This method permitted the expeditious and efficient synthesis of the anticancer 3-arylindanone 5 in two operative steps in 43% overall yield.pt_BR
dc.identifier.citationTAYLOR, J. G.; RIBEIRO, R. da S.; CORREIA, C. R. D. Facile synthesis of symmetrical 3,3-diarylacrylates by a Heck-Matsuda reaction: an expedient route to biologically active indanones. Tetrahedron Letters, v. 52, p. 3861-3864, 2011. Disponível em: <http://www.sciencedirect.com/science/article/pii/S0040403911007763>. Acesso em: 02 fev. 2015.pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.tetlet.2011.05.039
dc.identifier.issn0040-4039
dc.identifier.urihttp://www.repositorio.ufop.br/handle/123456789/4979
dc.language.isoen_USpt_BR
dc.rights.licenseO periódico Tetrahedron Letters concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3581340458166.pt_BR
dc.subjectArenediazonium tetrafluoroboratespt_BR
dc.subjectHeck-Matsudapt_BR
dc.subjectArylationpt_BR
dc.subjectIndanonespt_BR
dc.subjectPalladiumpt_BR
dc.titleFacile synthesis of symmetrical 3,3-diarylacrylates by a Heck-Matsuda reaction : an expedient route to biologically active indanones.pt_BR
dc.typeArtigo publicado em periodicopt_BR
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