Relation between uric acid and metabolic syndrome in subjects with cardiometabolic risk.
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Date
2015
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Abstract
Objective: To identify possible relations between serum uric acid
levels and metabolic syndrome and its components in a population
with cardiometabolic risk. Methods: This cross-sectional study
included 80 subjects (46 women), with mean age of 48±16 years,
seen at the Cardiovascular Health Program. Results: The prevalence
of hyperuricemia and metabolic syndrome was 6.3% and 47.1%,
respectively. Uric acid level was significantly higher in individuals with
metabolic syndrome (5.1±1.6mg/dL), as compared to those with
no syndrome or with pre-syndrome (3.9±1.2 and 4.1±1.3mg/dL,
respectively; p<0.05). The uric acid levels were significantly higher in
men presenting abdominal obesity, and among women with abdominal
obesity, lower HDL-c levels and higher blood pressure (p<0.05).
Conclusion: Uric acid concentrations were positively related to the
occurrence of metabolic syndrome and its components, and there were
differences between genders. Our results indicate serum uric acid as a
potential biomarker for patients with cardiometabolic risk.
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Keywords
Uric acid, Abdominal obesity, Metabolic diseases, Cardiovascular diseases/metabolism
Citation
SILVA, H. A. da et al. Relation between uric acid and metabolic syndrome in subjects with cardiometabolic risk. Einstein, v. 13, n. 2, p. 202-208, 2015. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082015005053194&lng=en&nrm=iso&tlng=en>. Acesso em: 29 ago. 2017.