Leishmania (Viannia) braziliensis : immunoblotting analysis for the detection of IgG subclasses in the diagnosis of symptomatic and asymptomatic dogs.

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dc.contributor.authorZanini, Marcos Santos
dc.contributor.authorViana, Kelvinson Fernandes
dc.contributor.authorReis, Alexandre Barbosa
dc.contributor.authorCampos, Diefrey Ribeiro
dc.contributor.authorMussi, Jamili Maria Suhet
dc.contributor.authorZanini, Surama
dc.contributor.authorLemos, Elenice Moreira
dc.date.accessioned2012-07-04T16:36:25Z
dc.date.available2012-07-04T16:36:25Z
dc.date.issued2010
dc.description.abstractDuring a seroepidemiological survey 2004–2006 from areas in Brazil endemic for American cutaneous leishmaniasis (ACL), serum samples from 10 dogs with ulcerated cutaneous lesions (S-ACL) and 52 asymptomatic dogs (AS-ACL) of unknown age and breed living in areas endemic for ACL were monitored for 1 year for ulcerated cutaneous lesions and immunoblotting using peroxidase-conjugated secondary anti-IgG, anti-IgG1 and anti-IgG2 dog antibodies. We reported that antibodies against Leishmania (Viannia) braziliensis in the sera of 22/52 dogs with asymptomatic disease showed intense reactivity to pep tides larger than 66 kDa. We believe that dogs harboring subclinical amastigotes show an immunoblotting profile similar to that of symptomatic animals because a dog with self-healing presented antigens greater than 66 kDa. Such patterns can be exploited for diagnostic and epidemiological research for leishmaniasis.pt_BR
dc.identifier.citationZANINI, M. S. et al. Leishmania (Viannia) braziliensis : immunoblotting analysis for the detection of IgG subclasses in the diagnosis of symptomatic and asymptomatic dogs. Veterinary Parasitology, v. 173, n. 1, p. 143-146, 2010. Disponível em: <https://www.sciencedirect.com/science/article/pii/S0304401710003353>. Acesso em: 04 jul. 2012.pt_BR
dc.identifier.issn03044017
dc.identifier.urihttp://www.repositorio.ufop.br/handle/123456789/965
dc.language.isoen_USpt_BR
dc.rights.licenseO periódico Veterinary Parasitology concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3291401258926.
dc.subjectAmericans cutaneous leishmaniasispt_BR
dc.subjectDogspt_BR
dc.subjectImmunoblotingpt_BR
dc.titleLeishmania (Viannia) braziliensis : immunoblotting analysis for the detection of IgG subclasses in the diagnosis of symptomatic and asymptomatic dogs.pt_BR
dc.typeArtigo publicado em periodicopt_BR
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