Microwave-promoted synthesis of chiral pyridinium salts.

Abstract
The synthesis of several chiral pyridinium salts via Zincke_s reaction can be easily accomplished by domestic microwave oven irradiation. Yield enhancements, reduction of reaction time, and less racemization were observed under microwave heating when compared to conventional heating in similar conditions.
Description
Keywords
Asymmetric synthesis, Amino alcohols, Pyridines, Microwave irradiation, Zincke's reaction
Citation
VIANA, G. H. R. et al. Microwave-promoted synthesis of chiral pyridinium salts. Tetrahedron Letters, v. 46, p. 7773-7776, 2005. Disponível em: <http://www.sciencedirect.com/science/article/pii/S004040390501991X>. Acesso em: 02 fev. 2015.