Development and characterization of medical phantoms for ultrasound imaging based on customizable and mouldable polyvinyl alcohol cryogel–based materials and 3-D printing : application to high-frequency cranial ultrasonography in infants.

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dc.contributor.authorElvira, Luis
dc.contributor.authorDurán, Carmen
dc.contributor.authorHiguti, Ricardo Tokio
dc.contributor.authorTiago, Marcelo Moreira
dc.contributor.authorIbáñez, Alberto
dc.contributor.authorParrilla, Montserrat
dc.contributor.authorValverde, Eva
dc.contributor.authorJiménez, Javier
dc.contributor.authorBassat, Quique
dc.date.accessioned2020-10-30T18:40:02Z
dc.date.available2020-10-30T18:40:02Z
dc.date.issued2019pt_BR
dc.description.abstractThis work presents an affordable and easily customizable methodology for phantom manufacturing, which can be used to mimic different anatomic organs and structures. This methodology is based on the use of polyvinyl alcohol–based cryogels as a physical substitute for biologic soft tissues and of 3-D printed polymers for hard tissues, moulding and supporting elements. Thin and durable soft-tissue mimicking layers and multilayer arrangements can be obtained using these materials. Special attention was paid to the acoustic properties (sound speed, attenuation coefficient and mechanical impedance) of the materials developed to simulate soft tissues. These properties were characterized as a function of the additives concentration (propylene-glycol and alumina particles). The polyvinyl alcohol formulation proposed in this work is stable over several freeze-thaw cycles, allowing the manufacturing of multilayer materials with controlled properties. The manufacturing methodology presented was applied to the development of a phantom for high-frequency cranial ultrasonography in infants. This phantom was able to reproduce the main characteristics of the ultrasound images obtained in neonates through the anterior fontanel, down to 8-mm depth.pt_BR
dc.identifier.citationELVIRA, L. et al. Development and characterization of medical phantoms for ultrasound imaging based on customizable and mouldable polyvinyl alcohol cryogel–based materials and 3-D printing: application to high-frequency cranial ultrasonography in infants. Ultrasound in Medicine & Biology, v. 45, n. 8, p. 2226-2241, ago. 2019. Disponível em: <https://www.umbjournal.org/article/S0301-5629(19)30188-7/fulltext>. Acesso em: 10 mar. 2020.pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.ultrasmedbio.2019.04.030pt_BR
dc.identifier.issn0301-5629
dc.identifier.urihttp://www.repositorio.ufop.br/handle/123456789/12902
dc.identifier.uri2https://www.umbjournal.org/article/S0301-5629(19)30188-7/fulltextpt_BR
dc.language.isoen_USpt_BR
dc.rightsrestritopt_BR
dc.subjectAcoustical characterizationpt_BR
dc.titleDevelopment and characterization of medical phantoms for ultrasound imaging based on customizable and mouldable polyvinyl alcohol cryogel–based materials and 3-D printing : application to high-frequency cranial ultrasonography in infants.pt_BR
dc.typeArtigo publicado em periodicopt_BR
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