Diagnosis of Schistosoma mansoni infections : what are the choices in Brazilian low-endemic areas?
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Date
2019
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Abstract
The population of Brazil is currently characterised by many individuals harbouring low-intensity Schistosoma mansoni infections. The Kato-Katz technique is the diagnostic method recommended by the World Health Organization (WHO) to assess these infections, but this method is not sensitive enough in the context of low egg excretion. In this regard, potential alternatives are being employed to overcome the limits of the Kato-Katz technique. In the present review, we evaluated the performance of parasitological and immunological approaches adopted in Brazilian areas. Currently, the diagnostic choices involve a combination of strategies, including the utilisation of antibody methods to screen individuals and then subsequent confirmation of positive
cases by intensive parasitological investigations.
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Keywords
Immunoassay, Point-of-care circulating cathodic antigen test - POC-CCA®
Citation
MORAES, V. S. et al. Diagnosis of Schistosoma mansoni infections: what are the choices in Brazilian low-endemic areas? Memórias do Instituto Oswaldo Cruz, v. 114, p. e180478, fev. 2019. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762019000100200>. Acesso em: 10 fev. 2020.