CXCL-16, IL-17, and bone morphogenetic protein 2 (BMP-2) are associated with overweight and obesity conditions in middle-aged and elderly women.
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Date
2017
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Abstract
The current concept of overweight/obesity is most likely related to a combination of increased caloric
intake and decreased energy expenditure. Widespread inflammation, associated with both conditions, appears to
contribute to the development of some obesity-related comorbidities. Interventions that directly or indirectly target
individuals at high risk of developing obesity have been largely proposed because of the increasing number of
overweight/obese cases worldwide. The aim of the present study was to assess CXCL16, IL-17, and BMP-2 plasma
factors in middle-aged and elderly women and relate them to an overweight or obese status. In total, 117 women
were selected and grouped as eutrophic, overweight, and obese, according to anthropometric parameters. Analyses
of anthropometric and circulating biochemical parameters were followed by plasma immunoassays for CXCL-16, IL-
17, and BMP-2.
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Keywords
Inflammation, Elderly, Overweight, Obesity
Citation
RIBEIRO, S. M. L. T. et al. CXCL-16, IL-17, and bone morphogenetic protein 2 (BMP-2) are associated with overweight and obesity conditions in middle-aged and elderly women. Immunity & Ageing, v. 14, p. 1-7, 2017. Disponível em: <https://immunityageing.biomedcentral.com/articles/10.1186/s12979-017-0089-0>. Acesso em: 16 jan. 2018.