The overweight increases circulating inflammatory mediators commonly associated with obesity in young individuals.

Simple item page
dc.contributor.authorLopes, Laís Roquete
dc.contributor.authorRibeiro, Silvana Mara Luz Turbino
dc.contributor.authorFigueiredo, Vivian Paulino
dc.contributor.authorLeite, Ana Luísa Junqueira
dc.contributor.authorNicolato, Roney Luiz de Carvalho
dc.contributor.authorEstanislau, Juliana de Assis Silva Gomes
dc.contributor.authorOliveira, Fernando Luiz Pereira de
dc.contributor.authorSilva, André Talvani Pedrosa da
dc.date.accessioned2019-04-02T17:23:25Z
dc.date.available2019-04-02T17:23:25Z
dc.date.issued2018
dc.description.abstractObesity is a serious and growing world healthy problem affecting developed and developing countries. The new conception of obesity as a basal inflammatory condition has opened a new window of possibilities to identify inflammatory biomarkers to be used in the diagnosis or prognosis of obesity-associated comorbidities. This present work aims the identification of the adipokines (leptin and resistin), chemokines (CCL2, CCL5, CXCL16) and the BMP-2 and their association with the clinical, biochemical (fasting glucose, hemogram, cholesterol, T3, T4 and TSH) and anthropometric (weight, height, body circumferences, skinfold thickness and percentage of body fat) parameters in young adults (18–30 years old) presenting obesity and overweight. Our data showed increasing in anthropometric parameters and in the plasma inflammatory levels in those individuals presenting overweight and obesity. We observed a higher plasma levels of CCL2, CCL5, CXCL16, leptin and resistin in those overweigh and obese individuals. In addition, the CCL2, CCL5 presented a positive correlation with the body mass index and the body fat percentage. Assuming the obesity as a systemic inflammatory process, in this current study, the overweight individuals possess a close similar pattern of circulating inflammatory mediators which might be a potential risk of the development of obesity comorbidities. Further studies are still needed to precise the role of the biomarkers CCL2, CCL5, CXCL16 and BMP-2 in the clinical prognosis related to the overweight or obese individuals.pt_BR
dc.identifier.citationLOPES, L. R. et al. The overweight increases circulating inflammatory mediators commonly associated with obesity in young individuals. Cytokine, v. 110, p. 169-173, out. 2018. Disponível em: <https://www.sciencedirect.com/science/article/pii/S1043466618301777?via%3Dihub>. Acesso em: 22 fev. 2019.pt_BR
dc.identifier.issn 10434666
dc.identifier.urihttp://www.repositorio.ufop.br/handle/123456789/10901
dc.identifier.uri2https://www.sciencedirect.com/science/article/pii/S1043466618301777pt_BR
dc.language.isoen_USpt_BR
dc.rightsrestritopt_BR
dc.subjectObesitypt_BR
dc.subjectInflammatory biomarkerspt_BR
dc.subjectAdipokinespt_BR
dc.subjectChemokinespt_BR
dc.titleThe overweight increases circulating inflammatory mediators commonly associated with obesity in young individuals.pt_BR
dc.typeArtigo publicado em periodicopt_BR
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
ARTIGO_OverweightIncreasesCirculating.pdf
Size:
622.61 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
924 B
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
DECBI - Artigos publicados em periódicos