Immunoreactivity of proteins within 30-40 kDa range during the acute and the recovery phases in rats experimentally infected with Strongyloides venezuelensis.

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dc.contributor.authorFonseca, Priscilla Duarte Marques
dc.contributor.authorCorral, Marcelo Andreetta
dc.contributor.authorMeisel, Dirce Mary Correia Lima
dc.contributor.authorLevi, Debora
dc.contributor.authorNascimento, Rafael Correa
dc.contributor.authorBorges, William de Castro
dc.contributor.authorGryschek, Ronaldo Cesar Borges
dc.contributor.authorCruz, Julia Maria Costa
dc.contributor.authorPaula, Fabiana Martins de
dc.date.accessioned2021-11-24T18:45:29Z
dc.date.available2021-11-24T18:45:29Z
dc.date.issued2020pt_BR
dc.description.abstractIn experimental infection with Strongyloides venezuelensis, the acute and recovery phases can be distinguished, unlike human infections caused by Strongyloides stercoralis. The objective of this study was to evaluate the production of anti-Strongyloides IgG antibodies and the recognition of immunogenic protein bands during the acute and the recovery phases in rats experimentally infected with S. venezuelensis. Rats were infected subcutaneously with 400 or 4,000 S. venezuelensis infective larvae. The acute phase was characterized by elimination of a large number of eggs in the faeces on days 6-14 post infection; the recovery phase was characterized by the resolution of the infection between days 30 and 35 post infection. Differences in IgG levels were observed in the acute and the recovery phases. Different antigenic fractions were recognized in both phases of infection. It is concluded that proteins within the 30-40 kDa range are immunoreactive markers for both the acute and the recovery phases in rats experimentally infected with S. venezuelensis, particularly using membrane antigen.pt_BR
dc.identifier.citationFONSECA, P. D. M. et al. Immunoreactivity of proteins within 30-40 kDa range during the acute and the recovery phases in rats experimentally infected with Strongyloides venezuelensis. Revista do Instituto de Medicina Tropical de São Paulo, v. 62, p. e23, 2020. Disponível em: <https://www.scielo.br/j/rimtsp/a/cGfbQ3v6p8WFtMMGJFnxPSt/?lang=en>. Acesso em: 10 jun. 2021.pt_BR
dc.identifier.doihttps://doi.org/10.1590/S1678-9946202062023pt_BR
dc.identifier.issn1678-9946
dc.identifier.urihttp://www.repositorio.ufop.br/jspui/handle/123456789/14030
dc.language.isoen_USpt_BR
dc.rightsabertopt_BR
dc.rights.licenseThis is an open-access article distributed under the terms of the Creative Commons Attribution License. Source: The article PDF.pt_BR
dc.titleImmunoreactivity of proteins within 30-40 kDa range during the acute and the recovery phases in rats experimentally infected with Strongyloides venezuelensis.pt_BR
dc.typeArtigo publicado em periodicopt_BR
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