Taylor, Jason GuyRibeiro, Rodrigo da SilvaCorreia, Carlos Roque Duarte2015-04-092015-04-092011TAYLOR, J. G.; RIBEIRO, R. da S.; CORREIA, C. R. D. Facile synthesis of symmetrical 3,3-diarylacrylates by a Heck-Matsuda reaction: an expedient route to biologically active indanones. Tetrahedron Letters, v. 52, p. 3861-3864, 2011. Disponível em: <http://www.sciencedirect.com/science/article/pii/S0040403911007763>. Acesso em: 02 fev. 2015.0040-4039http://www.repositorio.ufop.br/handle/123456789/4979A simple and straightforward synthesis of symmetrical 3,3-diarylacrylates based on a Heck-Matsuda reaction of arenediazonium salts bearing electron-donating groups with methylacrylates is described. The reaction employs Pd(OAc)2 as catalyst and goes to completion within 1 h affording the corresponding unsaturated diaryl esters in good to high yields. This method permitted the expeditious and efficient synthesis of the anticancer 3-arylindanone 5 in two operative steps in 43% overall yield.en-USArenediazonium tetrafluoroboratesHeck-MatsudaArylationIndanonesPalladiumArtigo publicado em periodicoO periódico Tetrahedron Letters concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3581340458166.https://doi.org/10.1016/j.tetlet.2011.05.039