Camargos, Adonai Bruneli deFonseca, Yasmim Arantes daSilva, Nayara Clarisse SoaresBarreto, Elisa da SilvaHerrera Adarme, Oscar FernandoParanhos, Aline Gomes de OliveiraGurgel, Leandro Vinícius AlvesBaêta, Bruno Eduardo Lobo2023-05-222023-05-222021CAMARGOS, A. B. de et al. Production of biogas and fermentable sugars from spent brewery grains: evaluation of one- and two-stage thermal pretreatment in an integrated biorefinery. Journal of Environmental Chemical Engineering, v. 9, artigo 105960, 2021. Disponível em: <https://www.sciencedirect.com/science/article/pii/S2213343721009374>. Acesso em: 11 out. 2022.2213-3437http://www.repositorio.ufop.br/jspui/handle/123456789/16623In this study, the production of fermentable sugars and biogas from thermally pretreated brewer’s spent grains (BSGs) was investigated. There were two autohydrolysis conditions (C1-1S: 180 oC, 30 min, 5 mLH2O gBSG − 1 and C2- 1S: 180 oC, 60 min, 5 mLH2O gBSG − 1 ) which were evaluated, with and without a previous low severity pretreatment (80 oC, 10 min, 10 mLH2O gBSG − 1 ). The highest specific methane production (302.4 NLCH4 kgCOD − 1 ) and enzymatic hydrolysis yield (EHY of 98%, 50 FPU gBSG − 1 ) were obtained from the two-stage pretreatment, with the second stage operated at 180 ◦C for 60 min, 5 mLH2O gBSG − 1 . However, in the integrated process, the two-stage pre- treatment with the second stage performed at 180 ◦C for 30 min, and 5 mLH2O gBSG − 1 was the best condition to produce fermentable sugars from enzymatic hydrolysis of pretreated BSGs, using a lower enzyme loading (EHY of 93%, 25 FPU gBSG − 1 ). The burning of biogas produced from an anaerobic digestion of liquid fractions (hydroly- sates) generated after two-stage thermal pretreatment in a combined heat and power system can produce a net thermal energy of 1.71 MJ kgBSG dry basis − 1 and electrical energy of 0.392 kW h kgBSG dry basis − 1 .en-USrestritoAnaerobic digestionEnzymatic hydrolysisLignocellullosic biomassArtigo publicado em periodicohttps://www.sciencedirect.com/science/article/pii/S2213343721009374https://doi.org/10.1016/j.jece.2021.105960