Santos, Daniela Cristina dosGil, Rossimiriam Pereira de FreitasGil, Laurent FrédéricMarazano, Christian2015-04-172015-04-172001SANTOS, D. C. dos et al. An enantioselective synthesis of isoquinuclidines from 3-substituted chiral pyridinium salts. Tetrahedron Letters, v. 42, p. 6109-6111, 2001. Disponível em: <http://www.sciencedirect.com/science/article/pii/S0040403901011947>. Acesso em: 02 fev. 2015.0040-4039http://www.repositorio.ufop.br/handle/123456789/5124A new enantioselective approach to chiral isoquinuclidines, such as 15, 18 and 21, is reported. The key step of these syntheses is a cycloaddition between chiral dihydropyridines 14 or 20, now readily available from tetrahydropyridinium salts 6 or 11, and achiral dienophiles. The reaction proceeds with a very good endo-selectivity and moderate d.e.en-USArtigo publicado em periodicoO periódico Tetrahedron Letters concede permissão para depósito deste artigo no Repositório Institucional da UFOP. Número da licença: 3581981445773.https://doi.org/10.1016/S0040-4039(01)01194-7