Early signs of cardiac diastolic dysfunction in ovariectomized WKY and SHR female rats.
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Date
2018
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Abstract
Half of patients with heart failure (HF) have diastolic
dysfunction but preserved EF (> 50%; HFpEF). There is no
specific treatment. Aging populations, and particularly women, are
more widely concerned. Why are women more likely than men to
develop HFpEF? Despite possible limitations, small animal models
could provide comprehensive approaches to identify/test novel
therapeutic targets.
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Citation
MARTINS, T. de A. et al. Early signs of cardiac diastolic dysfunction in ovariectomized WKY and SHR female rats. Archives of Cardiovascular Diseases Supplements, v. 10, p. 198, 2018. Disponível em: <https://www.sciencedirect.com/science/article/pii/S1878648018300594>. Acesso em: 05 abr. 2018.