Photoprotective activity and increase of SPF in sunscreen formulation using lyophilized red propolis extracts from Alagoas.

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dc.contributor.authorAlmeida, Wanessa Aparecida da Silveira
dc.contributor.authorAntunes, Amanda dos Santos
dc.contributor.authorPenido, Ricardo Gonçalves
dc.contributor.authorCorrêa, Helen S. da G
dc.contributor.authorNascimento, Andréa Mendes do
dc.contributor.authorAndrade, Ângela Leão
dc.contributor.authorSantos, Vagner Rodrigues
dc.contributor.authorCazati, Thiago
dc.contributor.authorAmparo, Tatiane Roquete
dc.contributor.authorSouza, Gustavo Henrique Bianco de
dc.contributor.authorFreitas, Katia Michelle
dc.contributor.authorSantos, Orlando David Henrique dos
dc.contributor.authorSousa, Lucas Resende Dutra
dc.contributor.authorSantos, Viviane Martins Rebello dos
dc.date.accessioned2020-05-22T16:11:48Z
dc.date.available2020-05-22T16:11:48Z
dc.date.issued2019
dc.description.abstractThe excessive sun exposure, coupled with lack of sun protection represents one of the biggest risks to the occurrence of skin cancer and photoaging. Recent strategies for photoprotection have included the incorporation of natural antioxidant and anti-inflammatory compounds, into sunscreens, and the oral administration of natural antioxidant extracts. In this work, we use Brazilian red propolis extract because its antioxidant and anti-inflammatory activities. The aim of this work was to evaluate the sun protection factor and antioxidant activity of different hydroalcoholic extracts of red propolis (70% and 75%) prepared from lyophilized red propolis at room and high temperatures. The sun protection factor in vitro was determined by a spectrophotometric method developed by Mansur. The hydroalcoholic extracts of red propolis incorporated with Filter UVA-UVB 5% Gel Permulem TR-1 presented absorption in the UVB region. Also, the in vitro capacity of the hydroalcoholic extracts of red propolis to increase photoprotective activity of Filter UVA-UVB 5% Gel was evaluated. The hydroalcoholic extracts of red propolis incorporated presented higher values of sun protection factor and showed synergism in the photoprotective activity of Filter UVA-UVB 5% Gel Permulem TR-1. The antioxidant activity and sun protection factor are correlated with total phenolics content of the extracts and the hydroalcoholic extract of red propolis 75% at room temperature was choosen. The formulation developed with Filter UVA-UVB 5% Gel Permulem TR-1 with this hydroalcoholic extract of red propolis showed safe to be applied on the skin according HET-CAM test. Suggests indication of hydroalcoholic extract of red propolis (75% – room temperature) associated to photoprotective formulations for use in photoprotective products.pt_BR
dc.identifier.citationALMEIDA, W. A. S. et al. Photoprotective activity and increase of SPF in sunscreen formulation using lyophilized red propolis extracts from Alagoas. Revista Brasileira de Farmacognosia, v. 29, n. 3, p. 373-380, jun. 2019. Disponível em:<https://www.sciencedirect.com/science/article/pii/S0102695X18305465>. Acesso em: 10 fev. 2020.pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.bjp.2019.02.003pt_BR
dc.identifier.issn0102-695X
dc.identifier.urihttp://www.repositorio.ufop.br/handle/123456789/12241
dc.language.isoen_USpt_BR
dc.rightsabertopt_BR
dc.rights.licenseThis is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Fonte: o próprio artigo.pt_BR
dc.subjectSun protection factorpt_BR
dc.subjectFilter UVA-UVBpt_BR
dc.subjectTotal phenolicspt_BR
dc.subjectAntioxidant activitypt_BR
dc.titlePhotoprotective activity and increase of SPF in sunscreen formulation using lyophilized red propolis extracts from Alagoas.pt_BR
dc.typeArtigo publicado em periodicopt_BR
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