On the application of knoevenagel condensation for the synthesis of benzylidene benzothiazine compounds and structural study.
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Date
2006
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Abstract
The synthesis and physico-chemical properties of new 6-acetylamino or 6-benzoyl-amino 2-benzylidene-4-methyl-4Hbenzo[1,4]thiazin-3-ones and 6-benzoylamino or 6-nitro 2-benzylidene-4H-benzo[1,4]thiazin-3-ones are described. These benzylidene benzothiazine compounds were prepared by the Knoevenagel condensation with benzaldehydes. The configurations and conformations of benzylidene benzothiazine derivatives were optimised using the semi-empirical method AM1.
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Keywords
Benzothiazines, Benzylidene benzothiazines, AM1 conformational and configurational analysis
Citation
SOUZA, A. M. A. et al. On the application of knoevenagel condensation for the synthesis of benzylidene benzothiazine compounds and structural study. QuĂmica Nova, v. 29, p. 1106-1109, 2006. DisponĂvel em: <http://www.scielo.br/scielo.php?pid=S0100-40422006000500035&script=sci_arttext> Acesso em: 20 ago. 2014.