Biological activities of extracts from Padina Boergesenii and Sargassum Stenophyllum, seaweeds naturally found in Baia de Todos os Santos, Brazil.

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dc.contributor.authorOliveira, Naiara Maia
dc.contributor.authorMeira, Carla Larissa Costa
dc.contributor.authorAguiar, Rosane Moura
dc.contributor.authorOliveira, Djalma Menezes de
dc.contributor.authorMoura, Carlos Wallace do Nascimento
dc.contributor.authorVieira Filho, Sidney Augusto
dc.date.accessioned2017-07-06T18:15:10Z
dc.date.available2017-07-06T18:15:10Z
dc.date.issued2015
dc.description.abstractObjective: Here we present the results of the biological potential as antioxidant, anti-cancer and leishmaniscidal from extracts of Padina boergesenii Allender & Kraft and of Sargassum stenophyllum Martius, seaweed species commonly found in bay of the Brazilian Atlantic coast named Baía de Todos os Santos, state Bahia. In addition, we reported on the chemical composition of extractive fractions from these algae. Methods: Phytochemicals prospecting methods such as thin layer chromatography (TLC) and spectrometry in the UV/Vis region were used to identify the chemical class of constituents from these algae extracts. Antioxidant potential of the fractions was evaluated using the α,α-diphenyl-β-picrylhydrazyl (DPPH) free radical scavenging method. The cytotoxic potential of seaweed extracts against the human breast cancer (MFC-7) cell lines was evaluated using the sulforhodamine B (SRB) colorimetric assay. The leishmanicidal effect of algae extracts against promastigotes of Leishmania amazonenses Laison & Shaw 1972 was evaluated using amphotericin B (AMB) as positive control. Results: Were detected flavonoids, steroids, carotenoids, anthocyanins and phenolic compounds from algae extracts in hexane, chloroform and n-butanol. Overall, extractive fractions showed moderate antioxidant activities in comparison with quecertin, butylated hydroxytoluene and gallic acid. Fractions from P. boergesenii and chloroform fraction of S. stenophyllum presented significant activity against MCF-7 cells by inhibiting the cells grown among 55.0 to 66.0 %. These results were closely similar to inhibition reached by colchicine (67.0 %) used as positive control. No antileishmanial significant effect was observed for P. boergesenii and S. stenophyllum extracts at the tested conditions. Conclusion: The results indicated a promissory pharmacologic potential for the P. boergesenii and S. stenophyllum extracts, Which open perspectives to the isolation of their active constituents.pt_BR
dc.identifier.citationOLIVEIRA, N. M. et al. Biological activities of extracts from Padina Boergesenii and Sargassum Stenophyllum, seaweeds naturally found in Baia de Todos os Santos, Brazil. International Journal of Pharmacy and Pharmaceutical Sciences, v. 7, p. 350-353, 2015. Disponível em: <https://innovareacademics.in/journals/index.php/ijpps/article/view/3540>. Acesso em: 16 jun. 2017.pt_BR
dc.identifier.issn0975-1491
dc.identifier.urihttp://www.repositorio.ufop.br/handle/123456789/8188
dc.identifier.uri2https://innovareacademics.in/journals/index.php/ijpps/article/view/3540pt_BR
dc.language.isoen_USpt_BR
dc.rightsrestritopt_BR
dc.subjectCell inhibitionpt_BR
dc.subjectAnti-Leishmaniapt_BR
dc.titleBiological activities of extracts from Padina Boergesenii and Sargassum Stenophyllum, seaweeds naturally found in Baia de Todos os Santos, Brazil.pt_BR
dc.typeArtigo publicado em periodicopt_BR
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